Bubble Up Biscuit Pizza Casserole Recipe

Irresistible Bubble Up Biscuit Pizza Casserole Recipe

Bubble up biscuit pizza casserole brings comfort food to a whole new level of deliciousness.

Hearty and satisfying, this dish combines familiar flavors in an unexpected twist that feels like a warm culinary hug.

Layers of soft, pillowy biscuits mingle with zesty pizza-inspired ingredients, creating a mouthwatering experience that converts ordinary ingredients into something extraordinary.

Families crave these crowd-pleasing meals that simplify weeknight dinner challenges while delivering maximum flavor.

Home cooks appreciate how quickly this casserole comes together with minimal preparation and maximum satisfaction.

Simple pantry staples convert into a crowd-pleasing meal that appeals to both kids and adults alike.

Everyone will be asking for seconds of this irresistible comfort classic.

What to Pair with Biscuit Pizza Casserole

  • Pair with Zesty Side Salad: Craft a crisp green salad with tangy vinaigrette to cut through the cheesy richness of the casserole. Toss mixed greens, cherry tomatoes, and cucumber for a refreshing contrast.
  • Match with Robust Red Wine: Select a medium-bodied red like Chianti or Sangiovese to complement the tomato sauce and cheesy flavors. The wine's acidity will balance the hearty casserole perfectly.
  • Serve with Cool Ranch Dressing: Drizzle cool ranch over individual servings to add a creamy, herbal dimension. This dressing brightens the dish and provides a smooth, tangy counterpoint to the baked pizza casserole.
  • Complement with Crisp Craft Beer: Choose a hoppy pale ale or light lager to refresh the palate between bites. The beer's carbonation will help cleanse the mouth after each cheesy, saucy mouthful.

Flavorful Twists on the Bubble-Up Bake

  • Spicy Southwest Bubble Up: Replace pizza sauce with salsa, swap mozzarella for pepper jack cheese, and add chorizo, black beans, and diced green chilies for a zesty southwestern kick.
  • Mediterranean Veggie Bubble Up: Use marinara sauce, sprinkle feta cheese, and top with chopped spinach, artichoke hearts, kalamata olives, and sun-dried tomatoes for a Mediterranean-inspired version.
  • Breakfast Pizza Bubble Up: Incorporate scrambled eggs, crispy bacon bits, diced ham, and cheddar cheese, then drizzle with hollandaise sauce after baking for a morning meal transformation.
  • Barbecue Chicken Bubble Up: Substitute pizza sauce with barbecue sauce, add shredded rotisserie chicken, red onions, and replace mozzarella with a blend of cheddar and monterey jack cheeses for a tangy, smoky flavor profile.

Why Bubble Up Biscuit Pizza Casserole Is So Fun and Filling

  • Whip Up Kid-Friendly Comfort: This casserole transforms classic pizza flavors into a fun, easy-to-eat meal that kids and adults will absolutely love, with bite-sized biscuit pieces making every scoop deliciously exciting.
  • Customize Your Culinary Adventure: The recipe offers incredible flexibility, letting you swap toppings based on family preferences, from classic pepperoni to veggie lovers or meat supreme options.
  • Speed-Slice Weeknight Dinner Solution: With just 30 minutes from prep to plate, this one-pan wonder delivers maximum flavor and minimum cleanup, perfect for busy families craving a satisfying meal without complicated cooking techniques.

What Goes in Bubble Up Biscuit Pizza Casserole

Main Pizza Components:
  • Refrigerated Buttermilk Biscuits: Convenient base for creating a quick and easy pizza casserole foundation, with soft and flaky texture that absorbs flavors well.
  • Pizza Sauce: Classic tomato-based sauce that provides rich, tangy flavor and moisture to the casserole, essential for authentic pizza taste.
Cheese:
  • Mozzarella Cheese: Creamy, melty cheese that creates a stretchy and gooey top layer, traditional in pizza-style dishes with mild and smooth flavor profile.
Pizza Toppings:
  • Pepperoni, Italian Sausage: Savory meat options that add protein and classic pizza flavor, with spicy and rich characteristics.
  • Bell Peppers, Onions: Fresh vegetables that contribute crunch, color, and additional layers of flavor to the casserole, providing nutritional variety and texture contrast.

How to Bake a Bubbly Biscuit-Base Pizza Casserole

Step 1: Prepare The Oven

Warm up your oven to 350°F. Coat a 9×13-inch baking dish with cooking spray or butter to prevent sticking.

Step 2: Slice Biscuit Dough

Open refrigerated buttermilk biscuit containers. Using a sharp pizza cutter or knife, chop each biscuit into:
  • Quarters
  • Small bite-sized chunks

Step 3: Create Biscuit Base

Spread biscuit pieces across the baking dish in a single layer. Place any overlapping pieces near the pan edges for faster cooking.

Step 4: Add Saucy Goodness

Generously pour pizza sauce over the biscuit pieces, ensuring complete coverage.

Step 5: Load Up Toppings

Sprinkle delicious toppings in this order:
  • Shredded mozzarella cheese
  • Pepperoni
  • Sliced mushrooms
  • Diced bell peppers
  • Chopped onions
  • Sliced olives

Step 6: Bake To Perfection

Cook uncovered for 25-30 minutes until:
  • Biscuit dough looks fully cooked
  • Cheese melts and turns golden brown
  • Center is hot and bubbly

Step 7: Cool And Serve

Let casserole rest for 5 minutes. Slice into generous portions and enjoy your pizza creation!

Tips for Gooey Cheese and Golden Biscuits

  • Slice Strategically: Cut biscuits into uniform quarters to ensure even cooking and consistent texture throughout the casserole.
  • Layer Wisely: Spread biscuit pieces in a single layer, concentrating slightly thicker pieces near pan edges for balanced baking.
  • Customize Creatively: Experiment with different pizza toppings like pepperoni, sausage, bell peppers, or olives to personalize the dish.
  • Check Center Carefully: Always verify the middle of the casserole is fully cooked by inserting a knife or toothpick to test doneness.
  • Cool Correctly: Let the casserole rest for at least 5 minutes after baking to allow cheese to set and prevent burning your mouth.

How to Store and Reheat Pizza Casserole Easily

  • Refrigerate: Transfer cooled casserole to an airtight container and store in the refrigerator for up to 3-4 days.
  • Reheat in Oven: Preheat oven to 350°F, cover with foil to prevent drying, and warm for 15-20 minutes until heated through.
  • Microwave Option: Heat individual portions on medium power for 1-2 minutes, checking halfway to ensure even warming and prevent soggy texture.
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Bubble Up Biscuit Pizza Casserole Recipe

Bubble Up Biscuit Pizza Casserole Recipe


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4.7 from 8 reviews

  • Total Time: 45 minutes
  • Yield: 6 1x

Description

Bubble Up Biscuit Pizza Casserole brings classic comfort to dinner tables with its irresistible blend of hearty biscuits, zesty pizza sauce, and melted cheese. Comfort seekers will devour this easy, crowd-pleasing dish that combines all the best pizza flavors in one satisfying casserole.


Ingredients

Scale

Main Ingredients:

  • 2 cans refrigerated buttermilk biscuits
  • 1 jar (15 ounces/425 grams) pizza sauce
  • 2 cups (480 milliliters) shredded mozzarella cheese

Protein/Topping Ingredients:

  • Pizza toppings of choice (pepperoni, Italian sausage, bell peppers, onions)

Instructions

  1. Prepare the oven by warming it to 350°F and coating a 9×13-inch baking vessel with a light grease layer to prevent sticking.
  2. Carefully dissect each refrigerated buttermilk biscuit into compact, uniform quarters using a sharp pizza cutter or knife.
  3. Construct a foundational layer of biscuit fragments across the baking dish, ensuring an even distribution with minimal overlapping, positioning any slightly stacked pieces toward the dish’s perimeter for optimal heat circulation.
  4. Generously ladle pizza sauce across the dough fragments, creating a vibrant crimson blanket that covers every morsel.
  5. Cascade shredded mozzarella cheese over the sauced surface, creating a delicate white landscape that will melt into creamy perfection.
  6. Embellish the cheese layer with selected pizza toppings, transforming the casserole into a personalized culinary canvas.
  7. Transfer the assembled dish into the preheated oven and bake uncovered for 25-30 minutes, monitoring the transformation until the biscuit base achieves a golden hue and the cheese bubbles with appetizing intensity.
  8. After removing from the oven, allow the casserole to rest and settle for approximately 5 minutes, enabling the ingredients to meld and cool slightly before serving.

Notes

  • Flexible recipe perfect for using random refrigerator ingredients like leftover meats, vegetables, or cheese varieties.
  • Customize toppings based on personal preferences or what’s available in your kitchen, making it a versatile meal solution.
  • Incredibly kid-friendly dish that transforms traditional pizza into a fun, easy-to-eat casserole format that reduces messy eating challenges.
  • Prep Time: 15 minutes
  • Cook Time: 30 minutes
  • Category: Dinner, Snacks
  • Method: Baking
  • Cuisine: American

Nutrition

  • Serving Size: 6
  • Calories: 400
  • Sugar: 5 g
  • Sodium: 900 mg
  • Fat: 22 g
  • Saturated Fat: 10 g
  • Unsaturated Fat: 8 g
  • Trans Fat: 0 g
  • Carbohydrates: 36 g
  • Fiber: 2 g
  • Protein: 15 g
  • Cholesterol: 40 mg
Isabella Rossi

Isabella Rossi

Founder & Culinary Content Creator

Expertise

Recipe Development​, Traditional Irish and European Cuisines, Food Styling and Photography, Culinary Education​

Education

Dublin Institute of Technology (DIT) – School of Culinary Arts and Food Technology

  • Degree: Bachelor of Arts in Culinary Arts
  • Focus: Comprehensive training in classical and modern cooking techniques, kitchen management, and menu development.​

Ballymaloe Cookery School

  • Program: 12-Week Certificate Course
  • Focus: Intensive, hands-on experience emphasizing farm-to-table cooking and sustainable practices.​

Liam is the voice behind many of Craft Meats’ most flavorful features. With roots in Dublin’s smoky barbecue scene and a culinary degree from the Dublin Institute of Technology, he brings time-tested cooking techniques to life. 

His training at Ballymaloe Cookery School sharpened his farm-to-table approach, giving him a deep respect for every ingredient he writes about.

He’s not about overcomplicating the process, just helping you cook meat that’s worth talking about. When he’s not writing or grilling, he’s out foraging or nerding out on regional spice blends to add to his next recipe.

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