Juicy Meatloaf Grilled Cheese Recipe: Comfort Sandwich Fusion

Comfort food reaches new heights with this irresistible meatloaf grilled cheese that combines two classic favorites into one mouthwatering dish.

Layers of tender, seasoned meatloaf nestle between golden, crispy bread slices oozing with melted cheese.

Crisp edges and a rich, savory interior make this sandwich a true crowd-pleaser for lunch or dinner.

The recipe marries the hearty flavors of traditional meatloaf with the gooey goodness of a perfectly grilled cheese.

Unexpected and delightful, this sandwich transforms leftover meatloaf into a culinary masterpiece.

Each bite promises a symphony of textures and tastes that will leave you craving more.

Dive into this delectable creation and elevate your sandwich game with a meal that’s sure to become a new family favorite.

Quick Recipe Overview

Prep Time: 10 minutes

Cook Time: 10 minutes

Total Time: 20 minutes

Calories: 700 kcal

Servings: 3

All Ingredients In Meatloaf Grilled Cheese

• Bread: Sturdy slices that provide a crispy, golden canvas for melting cheese and savory meatloaf.
• Butter: Transforms bread into a lusciously crisp, golden exterior with rich flavor.
• Garlic Powder: Optional zesty sprinkle that adds an aromatic punch to the sandwich's exterior.
• Ketchup: Tangy condiment that brings a sweet and slightly acidic note to complement the meat.
• Worcestershire Sauce: Adds depth and umami complexity when mixed with ketchup.

• Meatloaf: Hearty, pre-cooked protein that serves as the sandwich's substantial core.
• Cheddar Cheese: Sharp, melty cheese that provides a classic, robust dairy flavor.
• Provolone Cheese: Mild, smooth cheese that melts beautifully and adds creamy texture.
• Mozzarella Cheese: Stretchy alternative with a delicate, milky flavor profile.

• Tomato Soup: Classic comfort companion that perfectly complements the rich sandwich.
• Coleslaw: Crisp, tangy side that offers refreshing contrast to the warm, cheesy sandwich.
• Pickles: Zesty, crunchy addition that cuts through the sandwich's richness.

Tools To Make Meatloaf Grilled Cheese At Home

• Large skillet or griddle: Perfect for achieving that golden, crispy sandwich exterior.
• Spatula: Essential for flipping sandwiches and gently pressing them while cooking.
• Knife: Needed to slice bread and sandwiches after grilling.
• Cutting board: Provides a clean surface for bread preparation and slicing.
• Butter knife or spreader: Helps evenly distribute softened butter on bread slices.

How To Build Meatloaf Grilled Cheese Step-By-Step

• Warm Meatloaf

Grab your leftover meatloaf and heat it up gently in a skillet. The goal is to bring those savory slices back to life with a warm, inviting temperature.

• Bread Preparation

Select your favorite bread slices and spread softened butter across one side. A sprinkle of garlic powder can add a delightful twist to your sandwich canvas.

• Cheese and Layers

Create a delicious foundation by placing a slice of cheddar cheese on the bread. Top it with a warm meatloaf slice, then crown it with a slice of provolone. A quick swipe of ketchup adds a tangy kick to the inner layer.

• Grilling Magic

Place your sandwich in a heated skillet over medium warmth. Watch the magic happen as the bread turns golden and crispy while the cheese melts into gooey perfection. Gently press with a spatula to ensure even browning.

• Serving Time

Cut the sandwich diagonally for that classic deli look. Serve immediately while the cheese is still melted and the bread is crisp. A side of pickles or tomato soup makes this comfort meal complete.

Tasty Tips For Meatloaf Grilled Cheese Lovers

• Bread Choice Boost: Select sturdy bread like sourdough or Texas toast to prevent soggy sandwiches and provide extra crispy texture when grilled.
• Cheese Creativity: Experiment with different cheese combinations like Swiss, pepper jack, or blue cheese to add unique flavor profiles and personalize your sandwich experience.
• Healthier Twist: Replace traditional bread with low-carb alternatives like cauliflower bread or lettuce wraps for a lighter, gluten-free version that still delivers delicious taste.
• Vegetarian Transformation: Substitute meatloaf with grilled portobello mushrooms, plant-based meat alternatives, or roasted vegetable slices to create a satisfying vegetarian sandwich that maintains the original recipe's essence.
• Spice Level Enhancement: Add sriracha, jalapeños, or red pepper flakes inside the sandwich or mix into the ketchup spread to give your meatloaf grilled cheese an exciting, spicy kick that elevates the overall flavor profile.

Best Ways To Serve Meatloaf Grilled Cheese Warm

• Hearty Lunch Companion: Pair this meatloaf grilled cheese with a tangy tomato soup for a classic comfort food combination that warms your soul and satisfies hunger.
• Pickle Paradise: Serve alongside crisp dill pickles or quick-pickled vegetables to add a zesty, crunchy contrast to the rich, melty sandwich.
• Game Day Crowd-Pleaser: Cut the sandwich into smaller triangle sections for easy finger food during sports watch parties or casual gatherings with friends.
• Salad Sidekick: Balance the sandwich's richness with a light, fresh green salad dressed in a simple vinaigrette to create a well-rounded meal that doesn't feel too heavy.

Store Meatloaf Grilled Cheese Like A Pro

• Meal Prep Magic: Slice meatloaf into portion-sized pieces and store in airtight containers in the refrigerator for quick sandwich assembly during busy weekdays.
• Freezer-Friendly Hack: Wrap individual meatloaf slices in plastic wrap, then place in freezer bags for up to 3 months. Thaw overnight in the refrigerator before using.
• Bread Freshness Trick: Keep bread at room temperature in a sealed bag, away from direct sunlight and moisture. For extended storage, refrigerate to prevent molding.
• Cheese Care Strategy: Store cheese in the refrigerator's designated drawer, wrapped in wax paper or parchment to maintain optimal texture and prevent moisture buildup.

Hearty Meatloaf Grilled Cheese Recipe

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4.7 from 39 reviews

• Total Time: 20 minutes
• Yield: 3 1x

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Description

Hearty meatloaf grilled cheese sandwiches blend classic comfort foods into one irresistible meal. Melted cheese and savory meatloaf layers create a satisfying experience you’ll crave again and again.

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Ingredients

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• 8 slices bread (sourdough, brioche, or thick sandwich bread)
• 4 slices meatloaf (about 0.5-inch thick)
• 4 slices cheddar cheese
• 4 slices provolone or mozzarella cheese
• 4 tbsps (57 g) unsalted butter, softened
• ¼ cup (60 ml) ketchup (optional, for spreading)
• 1 tsp garlic powder (optional, for added flavor)
• 1 tsp Worcestershire sauce (optional, to mix with ketchup for a tangy kick)

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Instructions

1. Warm-Up: Gently reheat meatloaf slices in a skillet over medium heat or microwave, ensuring even warming for 2-3 minutes.
2. Bread Preparation: Lavishly coat bread slices with softened butter, optional garlic powder sprinkle for flavor enhancement.
3. Cheese Layer: Strategically place cheddar cheese on non-buttered bread surface, layer warm meatloaf slice, then crown with provolone cheese.
4. Flavor Boost: Spread ketchup or ketchup-Worcestershire sauce blend across interior of bread for tangy undertones.
5. Assembly: Carefully construct sandwich with buttered bread exterior facing outward.
6. Griddle Setup: Heat skillet or griddle to medium temperature, creating optimal grilling environment.
7. Grilling Process: Carefully position sandwiches, pressing gently with spatula to ensure uniform golden-brown caramelization and even melting.
8. Final Touch: Cook 3-4 minutes per side, monitoring for crispy exterior and fully melted cheese. Adjust heat to prevent burning.
9. Serving: Slice diagonally and present immediately alongside zesty tomato soup, tangy coleslaw, or crunchy pickles for a complete culinary experience.

Notes

• Reheat Meatloaf Carefully: Warm slices gently to maintain moisture and prevent drying out, using low-medium heat for even temperature distribution.
• Butter Strategically: Ensure butter is softened and evenly spread for consistent golden-brown crispiness and enhanced flavor absorption.
• Layer Cheese Thoughtfully: Place cheese directly against warm meatloaf to create maximum melting and flavor integration.
• Control Cooking Temperature: Monitor heat closely to achieve perfect golden-brown exterior without burning bread, adjusting skillet temperature as needed for ideal caramelization.

• Prep Time: 10 minutes
• Cook Time: 10 minutes
• Category: Lunch, Dinner, Snacks
• Method: Grilling
• Cuisine: American

Nutrition

• Serving Size: 3
• Calories: 700
• Sugar: 6 g
• Sodium: 1200 mg
• Fat: 38 g
• Saturated Fat: 20 g
• Unsaturated Fat: 15 g
• Trans Fat: 1 g
• Carbohydrates: 56 g
• Fiber: 2 g
• Protein: 36 g
• Cholesterol: 100 mg